A new finding in human physiology

Some original work in physiology and pharamacology – how sweating can be easily controlled by posture and  anti-inflammatory properties of anti-hypertensive drugs

When lying down after a late night as the ‘Cultural Secretary in 2nd year of Goa Medical College in the summer of 1986, I found that only one side of my body was sweating – the right side (when I was lying on the left) – and when I turned  to lie on the right, the left side started sweating – with a midline demarcation from head to toe. It was a very surprising finding as the ceiling fan was full on  in a hot and humid night and I did not expect the side facing the fan to sweat more or remain wet.

The next day, I tested this in my father and brother, and after searching for it in vain in all our textbooks, discussed it with our Professor of Physiology – Dr Ramesh A Dhume, asking him if this was a hitherto unknown physiological finding. He agreed and we applied for a student grant and performed an experiment – which proved this new finding to be real[1]

Other papers on physiology and pharmacology – written during medical school are on scientifically proven effects of meditation[2][3] and some new effects of common drugs[4]

[1] [pdf] J. Vaidya and R. Dhume, “Influence of lateral posture on sweating: does posture alter the sympathetic outflow to the sweat glands?,” Indian J Physiol Pharmacol, vol. 38, pp. 319-322, 1994.
[Bibtex]
@article{vaidya1994influenceglands,
author = "Vaidya, JS and Dhume, RA",
journal = "Indian J Physiol Pharmacol",
month = "Oct",
organization = "INDIA",
pages = "319--322",
title = "Influence of lateral posture on sweating: does posture alter the sympathetic outflow to the sweat glands?",
url = "http://www.ncbi.nlm.nih.gov/pubmed/7883305",
volume = "38",
year = "1994",
abstract = "Our unpublished observation that a lateral decubitus posture influences the pattern of sweating was systematically tested by measuring galvanic skin resistance (GSR). Changes in the GSR between two electrodes placed on skin was used to quantify the degree of sweating. In the lateral posture, sweating is inhibited on the lower half and stimulated on the upper half and reversal of the lateral posture induces sweating on the opposite half of the body. This observation suggests that the autonomic nervous system is controlled at least in part, by body posture.",
issn = "0019-5499",
issue = "4",
keyword = "Adolescent",
keyword = "Adult",
keyword = "Child",
keyword = "Galvanic Skin Response",
keyword = "Humans",
keyword = "Male",
keyword = "Middle Aged",
keyword = "Posture",
keyword = "Sweat Glands",
keyword = "Sweating",
keyword = "Sympathetic Nervous System",
language = "eng",
}
[2] J. Vaidya, R. Dhume, R. Dhume, and M. Gogate, “Effects of Meditation on muscle excitability revealed by changes in Strength duration curve during Shavasana,” Ind J Physiol Pharmacol, vol. 85, p. 86, 1984.
[Bibtex]
@article{vaidya1984effectsshavasana,
author = "Vaidya, JS and Dhume, RR and Dhume, RA and Gogate, MG",
journal = "Ind J Physiol Pharmacol",
pages = "86",
title = "Effects of Meditation on muscle excitability revealed by changes in Strength duration curve during Shavasana",
volume = "85",
year = "1984",
issue = "5",
}
[3] R. Dhume, J. Vaidya, R. Dhume, and M. Gogate, “Correlation of Muscle Activity(EMG), Muscle Excitability and Autonomic Changes induced during Meditation under Shavasana,” Ind J Physiol Pharmacol, vol. 85, pp. 87-87, 1984.
[Bibtex]
@article{dhume1984correlationshavasana,
author = "Dhume, RR and Vaidya, JS and Dhume, RA and Gogate, MG",
journal = "Ind J Physiol Pharmacol",
month = "Oct",
pages = "87--87",
title = "Correlation of Muscle Activity(EMG), Muscle Excitability and Autonomic Changes induced during Meditation under Shavasana",
volume = "85",
year = "1984",
issue = "5",
}
[4] [pdf] J. Vaidya, A. Jain, R. Diniz, N. Agshikar, and V. Dhume, “Anti-inflammatory activity of Furosemide and Spiranolactone,” Clinician, vol. 50, pp. 380-384, 1986.
[Bibtex]
@article{vaidya1986anti-inflammatoryspiranolactone,
author = "Vaidya, JS and Jain, A and Diniz, R and Agshikar, NV and Dhume, VG",
journal = "Clinician",
pages = "380--384",
title = "Anti-inflammatory activity of Furosemide and Spiranolactone",
volume = "50",
year = "1986",
issue = "11",
}