TARGIT literature archive

Pathological and biological rationale of partial breast irradiation (PBI) and the basis of the Targit Trial

1995    Hongkong International Cancer Congress

1996    British Journal of Cancer

1997    The Lancet

Could MRI be useful to select patients for breast conserving surgery?

1998    The Lancet (1)

1998    The Lancet (2)

 The Core trial Protocol of the Targit Trial

1999    The Lancet 

The UK Pilot Study of intraoperative radiation therapy: the first full paper about Targit

2001    Annals of Oncology

 The surgical technique of targeted intraoperative radiotherapy  (TARGIT) for early breast cancer treatment as used in the Targit trial

2002    European Journal of Surgical Oncology

2002    Surgical Technique Video

A possible one-stop out patient treatment for small breast cancers

2002    The Lancet

 PhD Thesis of Jayant S Vaidya

2002    University College London PhD Thesis

Some publicity

2000    BBC Tomorrow’s World

2001     Lancet Oncology News

2002    Time Magazine

2003    Reader’s Digest

2006    Reader’s Digest

 2003 San Antonio Breast Cancer Symposium:30-minute invited presentation about the Targit trial

2003    click here – this works

2003    Flash (SABCS Website)– not live any more.

Poster discussion about cosmetic results of the (Targit) intraoperative radiation therapy boost cases

2003    Cosmetic Outcome

Acute and Late Toxicity data about the Targit approach.

2004    ANZ Journal of Surgical Oncology

2005    Oncologie

2005    Tumori

2006    Int J Rad Oncol Biol Phys

Reviews, Editorial, Viewpoint

2004    Lancet Oncology

2004    British Journal of Radiology

2005    Seminas in Radiation Oncology

2006    Clinical Oncology 

2006    The Breast

2007    Nature Clinical Practice Oncology

2008    Annals of New York Academy of Sciences

Book Chapters  

2003    Recent Advances in Surgery

2006    Accelerated Partial Breast Irradiation (1st Edition)

2009    Accelerated Partial Breast Irradiation (2nd Edition)

 Radiobiology of Targeted intraoperation radiation therapy (TARGIT): Mathematical Modelling of breast cancer growth, recurrence and intra-operative radiotherapy (IORT) 

2005    Radiation Research

2005    Cancer Research UK Award Poster

2006    Journal of Theoretical Biology

2007    Journal of Theoretical Biology

 Targit under Local Anaesthetic

2006    World Journal of Surgical Oncology

 Targit boost :- results in a very low recurrence

2006    International Journal or Radiation Oncology Biology Physics

2008    American Society of Clinical Oncology (ASCO)

2010    International Journal or Radiation Oncology Biology Physics

5-yr actuarial = 1.73%  – half the expected recurrence rate

Novel effects of TARGIT on tumour micro-environment

2008    Clinical Cancer Research

2009    International Journal of Radiation Oncology Biology Physics

First publication of the main results

2010 The Lancet.  2010 ;376(9735):91-102.

Low radiation-related toxicity with TARGIT

2012 Breast Cancer Research and Treatment PDF

Cost-effectiveness of TARGIT 

2013 Annals of Surgical Oncology (PDF)   20:2873–2880

Better Cosmetic outcome from TARGIT

2003    San Antonio Breast Cancer Conference 

2013 Breast Cancer Research and Treatment (PDF)   140(3):519-25.

Better Quality of Life with TARGIT

2013 Radiation Oncology

Main 5-year results and first analysis of survival

2013 The Lancet, 11 November. doi:10.1016/s0140-6736(13)61950-9   PDF  Podcast