Pathological and biological rationale of partial breast irradiation (PBI) and the basis of the Targit Trial
1995 Hongkong International Cancer Congress
1996 British Journal of Cancer
Could MRI be useful to select patients for breast conserving surgery?
The Core trial Protocol of the Targit Trial
The UK Pilot Study of intraoperative radiation therapy: the first full paper about Targit
The surgical technique of targeted intraoperative radiotherapy (TARGIT) for early breast cancer treatment as used in the Targit trial
2002 European Journal of Surgical Oncology
A possible one-stop out patient treatment for small breast cancers
PhD Thesis of Jayant S Vaidya
2002 University College London PhD Thesis
Some publicity
2003 San Antonio Breast Cancer Symposium:30-minute invited presentation about the Targit trial
2003 Flash (SABCS Website)– not live any more.
Poster discussion about cosmetic results of the (Targit) intraoperative radiation therapy boost cases
Acute and Late Toxicity data about the Targit approach.
2004 ANZ Journal of Surgical Oncology
2006 Int J Rad Oncol Biol Phys
Reviews, Editorial, Viewpoint
2004 British Journal of Radiology
2005 Seminas in Radiation Oncology
2007 Nature Clinical Practice Oncology
2008 Annals of New York Academy of Sciences
Book Chapters
2003 Recent Advances in Surgery
2006 Accelerated Partial Breast Irradiation (1st Edition)
2009 Accelerated Partial Breast Irradiation (2nd Edition)
Radiobiology of Targeted intraoperation radiation therapy (TARGIT): Mathematical Modelling of breast cancer growth, recurrence and intra-operative radiotherapy (IORT)
2005 Cancer Research UK Award Poster
2006 Journal of Theoretical Biology
2007 Journal of Theoretical Biology
Targit under Local Anaesthetic
2006 World Journal of Surgical Oncology
Targit boost :- results in a very low recurrence
2006 International Journal or Radiation Oncology Biology Physics
2008 American Society of Clinical Oncology (ASCO)
2010 International Journal or Radiation Oncology Biology Physics
5-yr actuarial = 1.73% – half the expected recurrence rate
Novel effects of TARGIT on tumour micro-environment
2009 International Journal of Radiation Oncology Biology Physics
First publication of the main results
2010 The Lancet. 2010 ;376(9735):91-102.
Low radiation-related toxicity with TARGIT
2012 Breast Cancer Research and Treatment PDF
Cost-effectiveness of TARGIT
2013 Annals of Surgical Oncology (PDF) 20:2873–2880
Better Cosmetic outcome from TARGIT
2003 San Antonio Breast Cancer Conference
2013 Breast Cancer Research and Treatment (PDF) 140(3):519-25.
Better Quality of Life with TARGIT
Main 5-year results and first analysis of survival
2013 The Lancet, 11 November. doi:10.1016/s0140-6736(13)61950-9 PDF Podcast